Osimertinib Mesylate CAS 1421373-66-1 CAS NO.1421373-66-1

Name: Osimertinib Mesylate CAS 1421373-66-1
SKU: 1421373-66-1
Availability: InStock

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D-Ribose CAS#50-69-1 EINECS#200-059-4

CAS	1421373-66-1
MF	C29H37N7O5S
MW	595.71298
EINECS	200-064-1
Grade Standard	Medicine Grade, Tech Grade
Type	Auxiliaries and Other Medicinal Chemicals
Appearance	White Powder
Storage	Cool Dry Place
Application	Pharmaceutical Raw Intermediates
Description	Osimertinib is active against exon 19 deletions, exon 21 mutations, and also the exon 20 T790M mutations. It is preferentially selective for mutated EGFR, and therefore toxicity at therapeutic doses is lower than for first- and second-generation agents. Notably, osimertinib is able to cross the blood-brain barrier, making it active against disease in the CNS.
Definition	ChEBI: A methanesulfonate (mesylate) salt prepared from equimolar amounts of osimertinib and methanesulfonic acid. Used for treatment of EGFR T790M mutation positive non-small cell lung cancer.